Association of Testosterone Levels and Serum Iron in Patients With Liver Abscess at a Tertiary Care Center.

Background Bacteria or parasites, such as amoebic agents, are the primary causes of liver abscesses. The study was conducted to determine the relationship between serum iron profile and testosterone levels among participants who were diagnosed with amoebic liver abscess (ALA). Materials and methods This was a nonrandomized observational study. It was conducted from August 2023 to July 2024 at the Department of General Surgery, Indira Gandhi Institute of Medical Sciences (IGIMS), Patna, India. A total of 30 patients were included in the study. Results The mean age of all 30 patients was 45.6 ± 7.9 years. Levels of serum ferritin were 350.6 ± 47.9 ng/mL, total iron was 225.8 ± 62.9 mcg/dL, transferrin saturation was 62.1 ± 16.5%, total iron binding capacity was 612.5 ± 104.3 mcg/dL, and unfractionated iron binding capacity was 410.7 ± 97.5 mcg/dL among patients. Serum testosterone was found to be 1425.7 ± 283.4 ng/dL among patients. This study reported a strong positive correlation between serum testosterone and serum total iron levels among patients with a p-value of <0.001. Conclusion The study found that both serum testosterone and iron profile were elevated in patients with ALA. Further, more prospective studies are needed to support our results.