Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 1987
The effects of a constant T3 level and thermoneutrality in diet-induced hyperphagia.
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Abraham G, Falcou R, Rozen R, Mandenoff A, Autissier N, Apfelbaum M
Аннотация
Rats were thyroidectomized, then fitted with a miniosmotic pump infusing T3, thereby assuring a constant circulating level of T3. After a ten-day recovery period, they were submitted either to a chow or to a cafeteria diet. Body weight, food intake, and energy expenditure were recorded during a thirty day period. Thyroidectomized T3 supplemented rats did not exhibit hyperphagia when fed a cafeteria diet. Despite this puzzling normophagia, they still chose nutrients in a distribution similar to that of other cafeteria-fed rats and, though maintaining the same weight as chow-fed rats, increased their proportion of fatty weight compared to these rats. The relationship between energy expenditure, T3 concentration, and cafeteria diet are discussed.