Mayo Clinic proceedings · 1994
Paraneoplastic pemphigus: a case of prolonged survival.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
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Perniciaro C, Kuechle M K, Colón-Otero G, Raymond M G, Spear K L, Pittelkow M R
Аннотация
OBJECTIVE: To describe a patient with severe, recalcitrant mucous membrane erosions and chronic lymphocytic leukemia.
DESIGN: We present a case report and a literature review of paraneoplastic pemphigus.
MATERIAL AND METHODS: Immunofluorescence studies and immunoprecipitation confirmed the presence of autoantibodies characteristic of paraneoplastic pemphigus in the patient's serum.
RESULTS: Our patient lived almost 8 years after the onset of paraneoplastic pemphigus, the longest time that anyone with this disease is known to have survived.
CONCLUSION: The clinical course of paraneoplastic pemphigus tends to be rapid and fatal despite immunosuppressive therapy. Long-term survival is uncommon.
DESIGN: We present a case report and a literature review of paraneoplastic pemphigus.
MATERIAL AND METHODS: Immunofluorescence studies and immunoprecipitation confirmed the presence of autoantibodies characteristic of paraneoplastic pemphigus in the patient's serum.
RESULTS: Our patient lived almost 8 years after the onset of paraneoplastic pemphigus, the longest time that anyone with this disease is known to have survived.
CONCLUSION: The clinical course of paraneoplastic pemphigus tends to be rapid and fatal despite immunosuppressive therapy. Long-term survival is uncommon.