Obesity (Silver Spring, Md.) · 2015
Fetal epicardial fat thickness in diabetic and non-diabetic pregnancies: A retrospective cross-sectional study.
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Jackson Daniel, Deschamps David, Myers Dean, Fields David, Knudtson Eric, Gunatilake Ravindu
Аннотация
OBJECTIVE: To evaluate fetal epicardial fat thickness (EFT) in diabetic and control pregnancies.
METHODS: A retrospective cross-sectional study was performed in which fetal EFT was measured in the second trimester in 28 diabetics and 28 non-diabetic patients. Maternal BMI, estimated fetal weight, birth weight, fetal abdominal circumference, and subcutaneous fat thickness were also collected. Statistical analysis was carried out by means of chi-square, Wilcoxon rank-sum test, Student's T test, and linear regression as appropriate.
RESULTS: EFT was significantly higher in diabetic (1.43 mm) vs. control fetuses (1.16 mm), P = 0.02. This relationship remained significant when controlling for covariates.
CONCLUSIONS: EFT was higher in fetuses of diabetic mothers vs. fetuses from controls. If confirmed in prospective studies, this may represent a novel marker for altered fetal metabolism due to maternal diabetes.
METHODS: A retrospective cross-sectional study was performed in which fetal EFT was measured in the second trimester in 28 diabetics and 28 non-diabetic patients. Maternal BMI, estimated fetal weight, birth weight, fetal abdominal circumference, and subcutaneous fat thickness were also collected. Statistical analysis was carried out by means of chi-square, Wilcoxon rank-sum test, Student's T test, and linear regression as appropriate.
RESULTS: EFT was significantly higher in diabetic (1.43 mm) vs. control fetuses (1.16 mm), P = 0.02. This relationship remained significant when controlling for covariates.
CONCLUSIONS: EFT was higher in fetuses of diabetic mothers vs. fetuses from controls. If confirmed in prospective studies, this may represent a novel marker for altered fetal metabolism due to maternal diabetes.