Oral surgery, oral medicine, oral pathology and oral radiology · 2026
Nasopalatine duct cysts, case series of 106 cases with radiographic presentation and review of the literature.
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Buchanan Allison, Charmelo Scarlet, Namazi Farnaz, Richards Madison, Kalathingal Sajitha, Kurago Zoya, Abdelsayed Rafik
Аннотация
OBJECTIVES: To analyze 106 nasopalatine duct (NPD) cysts to identify characteristics that may indicate radiographic follow-up as a first line option.
STUDY DESIGN: Biopsy specimens were reviewed for gender, ethnicity, age, clinical presentation, treatment, size, and size vs symptoms. Ten cases (nine NPD cysts and one normal anatomical variant) with suitable documented radiographic imaging were selected to describe imaging features. Descriptive statistics were used to analyze gender, ethnicity, age, clinical presentation, size, size vs symptoms, gender vs symptoms, and size vs gender in symptomatic cases.
RESULTS: Most occurred in Caucasian males, most at ages 42-76. Gross specimen size was available for 102 cases with most measuring ≤15 mm (<10 mm = 21.6%; 10 mm = 26.5%; 11-15 mm = 28%; > 15 mm = 23.5%). Symptoms were reported rarely, 91% with symptoms measured ≥10 mm grossly. Most with symptoms occurred after age 45 and 43.5% occurred in females. Symptomatic NPD cysts were larger in males than females. Cases with imaging, width ranged from 7.8 to 12 mm on imaging and 78% occurred in males.
CONCLUSIONS: The data of this study validates existing literature reporting NPD cysts as non-aggressive and slow growing and suggests that there is a population of NPD cysts that are suitable for periodic follow-up. Combining size with symptoms and gender may help guide treatment decisions when radiographic findings are equivocal.
STUDY DESIGN: Biopsy specimens were reviewed for gender, ethnicity, age, clinical presentation, treatment, size, and size vs symptoms. Ten cases (nine NPD cysts and one normal anatomical variant) with suitable documented radiographic imaging were selected to describe imaging features. Descriptive statistics were used to analyze gender, ethnicity, age, clinical presentation, size, size vs symptoms, gender vs symptoms, and size vs gender in symptomatic cases.
RESULTS: Most occurred in Caucasian males, most at ages 42-76. Gross specimen size was available for 102 cases with most measuring ≤15 mm (<10 mm = 21.6%; 10 mm = 26.5%; 11-15 mm = 28%; > 15 mm = 23.5%). Symptoms were reported rarely, 91% with symptoms measured ≥10 mm grossly. Most with symptoms occurred after age 45 and 43.5% occurred in females. Symptomatic NPD cysts were larger in males than females. Cases with imaging, width ranged from 7.8 to 12 mm on imaging and 78% occurred in males.
CONCLUSIONS: The data of this study validates existing literature reporting NPD cysts as non-aggressive and slow growing and suggests that there is a population of NPD cysts that are suitable for periodic follow-up. Combining size with symptoms and gender may help guide treatment decisions when radiographic findings are equivocal.