The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2001
P300 in Behcet's patients without neurological manifestations.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Kececi H, Akyol M
Аннотация
OBJECTIVE: Behcet's disease is the association of recurrent aphthous stomatitis with genital ulceration and eye disease. Neurologic involvement patterns include meningomyelitis, a brain stem syndrome, pyramidal and extrapyramidal abnormality and stroke. In the present study, subclinical involvement was investigated by using P300 in Behcet's patients without neurological manifestation.
METHODS: Fifteen patients and 15 healthy volunteers were accepted for the study. P300 from vertex (Cz) electrode sites of the 10-20 system using electrodes and motor response time were recorded.
RESULTS: Patients had significantly prolonged latencies of P300 as compared to normal controls (p=0.013) but no significant differences in amplitude (p=1.000). Patients showed a significantly delayed motor response time than controls (p=0.006). Nine patients (60%) had P300 latency and eight patients (53.3%) had motor response time values exceeding the mean of controls by two standard deviations.
CONCLUSION: The findings suggest that the P300 measures and motor response time may reflect subclinical neurologic involvement in Behcet's disease.
METHODS: Fifteen patients and 15 healthy volunteers were accepted for the study. P300 from vertex (Cz) electrode sites of the 10-20 system using electrodes and motor response time were recorded.
RESULTS: Patients had significantly prolonged latencies of P300 as compared to normal controls (p=0.013) but no significant differences in amplitude (p=1.000). Patients showed a significantly delayed motor response time than controls (p=0.006). Nine patients (60%) had P300 latency and eight patients (53.3%) had motor response time values exceeding the mean of controls by two standard deviations.
CONCLUSION: The findings suggest that the P300 measures and motor response time may reflect subclinical neurologic involvement in Behcet's disease.