Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics · 2000
Intraoral digital imaging documenting recurrent aphthous ulcer healing in 2-octyl cyanoacrylate versus sham-treated lesions.
Клиническое исследованиеСравнительное исследованиеСтатьяРандомизированное исследованиеПоддержка службы здравоохранения СШАНазвание и аннотация: Перевод пока не подготовлен
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История · было → стало
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Ludlow J B, Kutcher M J, Samuelson A
Аннотация
OBJECTIVE: A device to standardize imaging was coupled with a digital intraoral camera to investigate the efficacy of 2-octyl cyanoacrylate (OC) tissue adhesives on the healing of minor aphthous ulcers.
STUDY DESIGN: Forty-two subjects were enrolled in a patient-blinded, sham-controlled study assessing the effects of 2-OC formulations on ulcer size and healing time. Daily images were made until ulcers were healed. Ulcer image outlines were traced by using a mouse, and ulcer areas were automatically calculated.
RESULTS: A mean difference of -0.15 mm(2) was seen between baseline and next-day measurements (P =.48). The cumulative ulcer area was meaningfully reduced in one OC group compared with the sham group (P =.04). Time to healing was reduced by 1.9 days in the same group compared with the sham group (P =.02).
CONCLUSIONS: The use of digital intraoral images with an integrated measurement reference enhances the accuracy and reproducibility of measurements. 2-OC adhesives hold promise as devices to promote healing of recurrent aphthous ulcers.
STUDY DESIGN: Forty-two subjects were enrolled in a patient-blinded, sham-controlled study assessing the effects of 2-OC formulations on ulcer size and healing time. Daily images were made until ulcers were healed. Ulcer image outlines were traced by using a mouse, and ulcer areas were automatically calculated.
RESULTS: A mean difference of -0.15 mm(2) was seen between baseline and next-day measurements (P =.48). The cumulative ulcer area was meaningfully reduced in one OC group compared with the sham group (P =.04). Time to healing was reduced by 1.9 days in the same group compared with the sham group (P =.02).
CONCLUSIONS: The use of digital intraoral images with an integrated measurement reference enhances the accuracy and reproducibility of measurements. 2-OC adhesives hold promise as devices to promote healing of recurrent aphthous ulcers.