Parkinsonism & related disorders · 2007
Essential tremor: phenotypic expression in a clinical cohort.
СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Whaley N R, Putzke John D, Baba Yasuhiko, Wszolek Zbigniew K, Uitti Ryan J
Аннотация
OBJECTIVES: Examine the characteristics of an essential tremor (ET) clinical cohort including base-rate variability of several commonly accepted diagnostic criteria.
METHODS: A clinical series of 487 consecutive individuals diagnosed with ET were included for study.
RESULTS: The sample was 53% male, had a mean age of onset of 52, and a mean age of 71. Half of the sample had a family history of ET. Half presented with asymmetrical disease and tremor affected the arms (97%), voice (62%), and head or neck (48%). There was considerable variability in the base rate of individuals fulfilling various commonly used diagnostic criteria of ET.
CONCLUSION: The sample was deemed representative of ET clinical cohorts. Asymmetric disease was common, and there was considerable base-rate variation across traditional ET diagnostic criteria.
METHODS: A clinical series of 487 consecutive individuals diagnosed with ET were included for study.
RESULTS: The sample was 53% male, had a mean age of onset of 52, and a mean age of 71. Half of the sample had a family history of ET. Half presented with asymmetrical disease and tremor affected the arms (97%), voice (62%), and head or neck (48%). There was considerable variability in the base rate of individuals fulfilling various commonly used diagnostic criteria of ET.
CONCLUSION: The sample was deemed representative of ET clinical cohorts. Asymmetric disease was common, and there was considerable base-rate variation across traditional ET diagnostic criteria.