Neurology · 2005
Incidence of essential tremor in three elderly populations of central Spain.
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Benito-León Julián, Bermejo-Pareja Félix, Louis Elan D, Neurological Disorders in Central Spain (NEDICES) Study Group
Аннотация
OBJECTIVE: To estimate the incidence of essential tremor (ET) in three populations in central Spain using data from the Neurologic Disorders in Central Spain (NEDICES), a population-based survey of elderly subjects (65 years and older).
METHODS: Individuals were evaluated at baseline (1994 to 1995) and at follow-up (a median of 3.3 years later in 1997 to 1998). The evaluation included a screening question for ET and a neurologic examination, when possible.
RESULTS: Of 5,278 subjects evaluated at baseline, there were 256 prevalent ET cases. Eighty-three incident ET cases were identified among 3,942 individuals assessed at follow-up. The adjusted annual incidence rate (per 100,000 person-years) in the population aged 65 years and older was 616 (95% CI: 447 to 784). Sixty-four (77.1%) of 83 incident cases had not been diagnosed before our assessment.
CONCLUSIONS: The incidence of ET may be higher than previously recognized because a large proportion of patients with ET may never seek medical attention.
METHODS: Individuals were evaluated at baseline (1994 to 1995) and at follow-up (a median of 3.3 years later in 1997 to 1998). The evaluation included a screening question for ET and a neurologic examination, when possible.
RESULTS: Of 5,278 subjects evaluated at baseline, there were 256 prevalent ET cases. Eighty-three incident ET cases were identified among 3,942 individuals assessed at follow-up. The adjusted annual incidence rate (per 100,000 person-years) in the population aged 65 years and older was 616 (95% CI: 447 to 784). Sixty-four (77.1%) of 83 incident cases had not been diagnosed before our assessment.
CONCLUSIONS: The incidence of ET may be higher than previously recognized because a large proportion of patients with ET may never seek medical attention.