Clinical Characteristics and Outcomes of Infective Endocarditis in Patients Undergoing Maintenance Hemodialysis　- A Retrospective Nationwide Database Analysis.

BACKGROUND

Patients with infective endocarditis (IE) on maintenance hemodialysis (HD) have poor outcomes, but contemporary data remain limited.

METHODS AND

RESULTS

We conducted a retrospective analysis using a nationwide Japanese administrative database and identified 12,158 patients hospitalized with IE between 2018 and 2021, including 806 (6.6%) on maintenance HD. The inhospital mortality rate was significantly higher in HD patients (30.0% vs. 13.5%, P<0.05).

CONCLUSIONS

Maintenance HD patients with IE had worse outcomes, underscoring the need for early recognition and tailored management in this highrisk group.