Journal of the American Academy of Dermatology · 1994
Histologic evaluation of chronic human wounds treated with hydrocolloid and nonhydrocolloid dressings.
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Phillips T J, Palko M J, Bhawan J
Аннотация
BACKGROUND: Studies of acute surgical wounds in pigs have shown granulomatous tissue reactions induced by hydrocolloid dressings.
OBJECTIVE: We examined biopsy specimens from chronic wounds in humans treated with hydrocolloid or nonhydrocolloid dressings to determine whether such reactions occurred.
METHODS: A blinded retrospective analysis of 22 chronic ulcer biopsy specimens from 22 patients was performed by two dermatopathologists independently.
RESULTS: No differences were seen between hydrocolloid-treated and non-hydrocolloid-treated wounds. Granulation tissue was seen in all specimens. No cavities, eosinophilic inclusions, polarizable material, or multinucleated giant cells were identified.
CONCLUSION: There are no significant histologic differences between hydrocolloid-treated and non-hydrocolloid-treated wounds in humans.
OBJECTIVE: We examined biopsy specimens from chronic wounds in humans treated with hydrocolloid or nonhydrocolloid dressings to determine whether such reactions occurred.
METHODS: A blinded retrospective analysis of 22 chronic ulcer biopsy specimens from 22 patients was performed by two dermatopathologists independently.
RESULTS: No differences were seen between hydrocolloid-treated and non-hydrocolloid-treated wounds. Granulation tissue was seen in all specimens. No cavities, eosinophilic inclusions, polarizable material, or multinucleated giant cells were identified.
CONCLUSION: There are no significant histologic differences between hydrocolloid-treated and non-hydrocolloid-treated wounds in humans.