[Effect of physical loading of various intensities on the thiamine allowance and ascorbic acid content of the blood and adrenals of rats of different ages].

Providing with thiamine and the content of ascorbic acid (AA) were studied in 250 male rats with respect to their age and depending on the duration of physical load. In all age groups (from 1 to 1.5 months, from 6 to 12 months and over 12 months) the physical load (swimming) led to a decrease of the body providing with thiamine, that was expressed in the reduction of its content in the blood and liver, in the lowering of transketolase activity and rising of the TDP effect. These changes were more pronounced at the early age and directly depended on the duration of physical load. Physical load induced more manifest reduction of the AA content in the blood of young rats, and in the adrenals of the older group animals. Vitamin B1 and C deficiency induced by high physical load necessitates its correction by administration of additional doses of the vitamins to the animals.