Internal medicine (Tokyo, Japan) · 2017
Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Miyamoto Shuichi, Kato Mototsugu, Matsuda Kana, Abiko Satoshi, Tsuda Momoko, Mizushima Takeshi, Yamamoto Keiko, Ono Shoko, Kudo Takahiko, Shimizu Yuichi, Hatanaka Kanako C, Tsunematsu Izumi, Sakamoto Naoya
Аннотация
A 56-year-old man with gastroesophageal reflux disease (GERD) was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed no evidence of any polypoid lesions in the stomach, and the patient had no history of Helicobacter pylori infection. He received omeprazole (20 mg) once daily for the GERD. EGD was performed at 1 year after the start of omeprazole administration, and this time, gastric hyperplastic polyps (GHPs) were detected. The GHPs increased in size as the omeprazole treatment continued, but they markedly decreased in size following omeprazole discontinuation. Thus, the administration of proton pump inhibitors may be a risk factor for the development of GHP independent of H. pylori infection.