Journal of human lactation : official journal of International Lactation Consultant Association · 2025
Antibiotic Resistance in Breastfeeding Diseases: A Multidisciplinary Study in an Italian Level III Medical Center.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pileri Paola, Coco Chiara, Lubrano Chiara, Mazzocco Martina Ilaria, Giani Sofia, Rimoldi Sara Giordana, Sartani Alessanda, Bottino Vanessa, Cetin Irene
Аннотация
BACKGROUND: Antimicrobial resistance is a global concern. It is particularly impactful during breastfeeding infections when identifying risk factors and protective mechanisms is crucial.
RESEARCH AIM: This study aimed to assess the prevalence of antibiotic resistance among breastfeeding women diagnosed with mastitis and breast abscesses.
METHODS: A cross-sectional analysis of longitudinal data was conducted at a Level III medical center in Italy from January 2016 to December 2020. A total of 203 women were enrolled following diagnoses of mastitis or breast abscesses.
RESULTS: Among the 156 women who tested positive for Staphylococcus aureus infection, culture antibiograms identified 29.6% as methicillin-resistant Staphylococcus aureus (MRSA). Additionally, six women exhibited clindamycin-resistant S. aureus. Exclusive breastfeeding at discharge (OR = 0.40, 95% CI [0.26, 0.84], p = 0.01) and rooming-in (OR = 0.34, 95% CI [0.15, 0.79], p = 0.01) were significantly associated with reduced odds of methicillin-resistant infections; although these findings are based on unadjusted odds ratios. Conversely, the use of breastfeeding aids in-hospital was not significantly associated with odds of resistant bacterial infections (OR 2.02, 95% CI [0.97, 4.18], p = 0.06).
CONCLUSION: This study underscores the antibiotic resistance scenario of microorganisms causing mastitis and abscesses in our setting. Implementing microbiological surveillance in mother-child settings could aid in identifying local resistance patterns.
RESEARCH AIM: This study aimed to assess the prevalence of antibiotic resistance among breastfeeding women diagnosed with mastitis and breast abscesses.
METHODS: A cross-sectional analysis of longitudinal data was conducted at a Level III medical center in Italy from January 2016 to December 2020. A total of 203 women were enrolled following diagnoses of mastitis or breast abscesses.
RESULTS: Among the 156 women who tested positive for Staphylococcus aureus infection, culture antibiograms identified 29.6% as methicillin-resistant Staphylococcus aureus (MRSA). Additionally, six women exhibited clindamycin-resistant S. aureus. Exclusive breastfeeding at discharge (OR = 0.40, 95% CI [0.26, 0.84], p = 0.01) and rooming-in (OR = 0.34, 95% CI [0.15, 0.79], p = 0.01) were significantly associated with reduced odds of methicillin-resistant infections; although these findings are based on unadjusted odds ratios. Conversely, the use of breastfeeding aids in-hospital was not significantly associated with odds of resistant bacterial infections (OR 2.02, 95% CI [0.97, 4.18], p = 0.06).
CONCLUSION: This study underscores the antibiotic resistance scenario of microorganisms causing mastitis and abscesses in our setting. Implementing microbiological surveillance in mother-child settings could aid in identifying local resistance patterns.