Медицинская библиотека · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2005

[The genotypic profiles of Candida albicans isolates from patients with oral lichen planus].

Zeng Xin, Chen Qian-ming, Nie Min-hai, Li Bing-qi

СтатьяПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

OBJECTIVE

The aim of this study was to investigate the genotypic profiles of Candida albicans isolates from erosive oral lichen planus (OLP) and non-erosive OLP.

METHODS

A total of 112 isolates obtained from healthy control (26), erosive OLP (62) and non-erosive OLP (24) were screened for genotypic profiles by using the randomly amplified polymorphic DNA (RAPD) assay.

RESULTS

RAPD analyses with some random primer reavealed 4 different genotypes among all isolates, and there was significant difference in genotypic constitution between every two groups. Statistically, B and D were the major types in healthy group; A and C were the major types in erosive OLP; A and D were the major types in non-erosive OLP.

CONCLUSION

Some Candida albicans isolates with special genotypic profiles may contribute to the development and progression of OLP.

Для цитирования: Zeng Xin, Chen Qian-ming, Nie Min-hai, Li Bing-qi. [The genotypic profiles of Candida albicans isolates from patients with oral lichen planus].. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2005.

Предметные рубрики MeSH

Candida albicans Candidiasis, Oral Genotype Humans Lichen Planus, Oral Random Amplified Polymorphic DNA Technique

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