Ectopic Insulinoma in the Pyloric Antrum Portion of the Stomach: A Case Report and Review of the Associated Diagnostic Challenges.

Ectopic insulinomas are rare neuroendocrine tumors that present with diagnostic challenges because of their atypical location. We report the case of a 64-year-old woman with recurrent hypoglycemia caused by an insulinoma originating from the gastric pyloric antrum. The diagnosis was confirmed through clinical assessment, biochemical testing, imaging studies, and a histopathological examination. Laparoscopic distal gastrectomy with D1 lymphadenectomy was performed to resolve the hypoglycemic episodes. This case highlights the importance of considering ectopic insulinomas in the differential diagnosis of unexplained cases of hypoglycemia, and it underscores the need for a multidisciplinary approach using advanced imaging and histopathological evaluations to make an accurate diagnosis and provide effective treatment.