Combination Antifungal Therapy and Formulary Optimization for Progressive Invasive Pulmonary Aspergillosis in a Pediatric Patient With Acute Myeloid Leukemia: A Case Report.

Therapeutic response in refractory invasive pulmonary aspergillosis may depend not only on antifungal class escalation, but also on formulation choice. In this complex pediatric acute myeloid leukemia (AML) case, radiologic improvement followed combination therapy and switch to brand-name liposomal amphotericin B, underscoring the importance of individualized antifungal optimization.