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DOI 10.1001/archdermatol.2009.358

Медицинская библиотека · Archives of dermatology · 2010

Successful treatment of atrophic postoperative and traumatic scarring with carbon dioxide ablative fractional resurfacing: quantitative volumetric scar improvement.

Weiss Elliot T, Chapas Anne, Brightman Lori, Hunzeker Christopher, Hale Elizabeth K, Karen Julie K, Bernstein Leonard, Geronemus Roy G

СтатьяПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

OBJECTIVE

To assess the safety and efficacy of ablative fractional resurfacing (AFR) for nonacne atrophic scarring.

DESIGN

In this before-and-after trial, each scar received 3 AFR treatments and 6 months of follow-up.

SETTING

Private academic practice.

PATIENTS: Fifteen women with Fitzpatrick skin types I to IV, aged 21 to 66 years, presented with 22 nonacne atrophic scars between June 1 and November 30, 2007. Three patients (3 scars) were excluded from the study after receiving 1 AFR treatment and not returning for follow-up visits. The remaining 12 patients (19 scars) completed all 3 treatments and 6 months of follow-up.

INTERVENTIONS: Each scar received 3 AFR treatments at 1- to 4-month intervals.

MAIN OUTCOME MEASURES: Erythema, edema, petechiae, scarring, crusting, and dyschromia were graded after treatment and through 6 months of follow-up. Skin texture, pigmentation, atrophy, and overall appearance were evaluated after treatment and through 6 months of follow-up by the patient and a nonblinded investigator. A 3-dimensional optical profiling system generated high-resolution topographic representations of atrophic scars for objective measurement of changes in scar volume and depth.

RESULTS

Adverse effects of treatment were mild to moderate, and no scarring or delayed-onset hypopigmentation was observed. At the 6-month follow-up visit, patient and investigator scores demonstrated improvements in skin texture for all scars (patient range, 1-4 [mean, 2.79]; investigator range, 2-4 [mean, 2.95]), pigmentation for all scars (patient range, 1-4 [mean, 2.32]; investigator range, 1-4 [mean, 2.21]), atrophy for all scars (patient range, 1-4 [mean, 2.26]; investigator range, 2-4 [mean, 2.95]), and overall scar appearance for all scars (patient range, 2-4 [mean, 2.89]; investigator range, 2-4 [mean, 3.05]). Image analysis revealed a 38.0% mean reduction of volume and 35.6% mean reduction of maximum scar depth.

CONCLUSION

The AFR treatments represent a safe, effective treatment modality for improving atrophic scarring due to surgery or trauma.

Для цитирования: Weiss Elliot T, Chapas Anne, Brightman Lori, Hunzeker Christopher, Hale Elizabeth K, Karen Julie K, Bernstein Leonard, Geronemus Roy G. Successful treatment of atrophic postoperative and traumatic scarring with carbon dioxide ablative fractional resurfacing: quantitative volumetric scar improvement.. Archives of dermatology. 2010. DOI: 10.1001/archdermatol.2009.358.

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