A long term clinical diagnostic-therapeutic evaluation of 30 case reports of bipolar spectrum mixed states.

The aim of this study is to show how managing long term patients who are diagnosed as having bipolar disorder with an affective mixed states can cause them to achieve a high level of recovery from the illness and quality of life. This study observed all consecutive new patients who were seen in a private psychiatry practice during the years 2008-2009-2010 who had a diagnosis within the mixed states sub-group (Irritable Cyclothymia, Mixed Disphoria and Agitated Depression)Thirty patients were selected who presented with a score of less than 40 on the Global Assessment Scale (GAS). They were reassessed by readministering the GAS scale after six months and after two years treatment. The final results demonstrate an improvement of the mood of the patients and their increasing quality of life. Almost all reached a value on the GAS scale of between 60 and 80 after six months, and between 90 and 100 scores after two years.