Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025
SCORE 2 and SCORE 2-OP Risk Scales as Prognostic Factors After Sudden Idiopathic Hearing Loss.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
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Say Mehmet Ali, Çakan Fahri, Yiğit Volkan Bilge
Аннотация
OBJECTIVES: This study aimed to investigate whether the Systematic Coronary Risk Estimation 2 and Systematic Coronary Risk Estimation 2-Older Persons (SCORE 2 and SCORE 2-OP) cardiovascular disease (CVD) risk scales can be used as prognostic factor for sudden sensorineural hearing loss (SSHL).
DESIGN: Prospective observational study.
SETTING: Single-center study.
METHODS: The study included 62 patients diagnosed with SSHL. SCORE 2 and SCORE 2-OP risks were calculated using the data collected from each participant. Patients were categorised into Green (low-moderate) and Non-Green (Yellow and Red, containing high and very high) risk groups. Recovery was categorised based on changes in pure-tone average (PTA). Statistical analyses included Pearson's correlation, univariate and multivariate logistic regression and ROC curve analysis.
RESULTS: A significantly higher proportion of patients in the Complete Recovery group had a Green SCORE risk classification (63.6%) than in the non-complete recovery group (32.5%, p = 0.018). The Green SCORE classification and lower pre-treatment PTA levels were significantly associated with better recovery outcomes. In multivariate analysis, Green SCORE remained an independent predictor of complete recovery (OR = 4.052, 95% CI: 1.218-13.487, p = 0.023). ROC analysis revealed moderate discriminative ability (AUC = 0.656, p = 0.044; sensitivity, 63.6%; specificity, 67.5%), with a negative predictive value of 77.1%.
CONCLUSION: The SCORE2 and SCORE2-OP cardiovascular risk scores, particularly the Green risk category, are valuable predictors of hearing recovery in SSHL. This finding has the potential to serve as a guide for clinicians, informing the adaptation of treatment intensity or the investigation of adjunctive therapies within populations characterised by elevated risk.
DESIGN: Prospective observational study.
SETTING: Single-center study.
METHODS: The study included 62 patients diagnosed with SSHL. SCORE 2 and SCORE 2-OP risks were calculated using the data collected from each participant. Patients were categorised into Green (low-moderate) and Non-Green (Yellow and Red, containing high and very high) risk groups. Recovery was categorised based on changes in pure-tone average (PTA). Statistical analyses included Pearson's correlation, univariate and multivariate logistic regression and ROC curve analysis.
RESULTS: A significantly higher proportion of patients in the Complete Recovery group had a Green SCORE risk classification (63.6%) than in the non-complete recovery group (32.5%, p = 0.018). The Green SCORE classification and lower pre-treatment PTA levels were significantly associated with better recovery outcomes. In multivariate analysis, Green SCORE remained an independent predictor of complete recovery (OR = 4.052, 95% CI: 1.218-13.487, p = 0.023). ROC analysis revealed moderate discriminative ability (AUC = 0.656, p = 0.044; sensitivity, 63.6%; specificity, 67.5%), with a negative predictive value of 77.1%.
CONCLUSION: The SCORE2 and SCORE2-OP cardiovascular risk scores, particularly the Green risk category, are valuable predictors of hearing recovery in SSHL. This finding has the potential to serve as a guide for clinicians, informing the adaptation of treatment intensity or the investigation of adjunctive therapies within populations characterised by elevated risk.