Letter to the editor involving the article 'Piriformis muscle syndrome: A cross-sectional imaging study in 116 patients and evaluation of therapeutic outcome'.

• Lack of use of local injection test to confirm the diagnosis may lead to miss the diagnosis of PMS of myofascial origin. • Piriformis muscle syndrome should be diagnosed on the basis of clinical symptoms, specific physical examinations, and positive response to local injection. • Sciatic nerve entrapment is not a must in the diagnosis of PMS and PMS is mostly myofascial in origin.