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DOI 10.1002/cam4.7031

Медицинская библиотека · Cancer medicine · 2024

Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study.

Malard Olivier, Karakachoff Matilde, Ferron Christophe, Hans Stéphane, Vergez Sébastien, Garrel Renaud, Gorphe Philippe, Ramin Lionel, Santini Laure, Villeneuve Alexandre, Lasne-Cardon Audrey, Espitalier Florent, Hounkpatin Audrey

СтатьяМногоцентровое исследованиеНаблюдательное исследованиеПеревод пока не подготовлен

Аннотация

BACKGROUND

Transoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy.

METHODS

A retrospective multicenter study (n = 138) in a previously irradiated area between 2009 and 2020. Survival was assessed with the Kaplan-Meier method. Prognostic factors were evaluated using a chi-squared test, Fisher's test, or Wilcoxon's test.

RESULTS

The median length of hospital stay was 12.5 days. Bleeding was the most frequent postoperative complication (15.2%, n = 22). Prophylactic vessel ligation did not significantly decrease bleeding. Complications were significantly lower for Tis, T1, and N0 tumors. 91.6% (n = 120) of the patients with a perioperative tracheotomy could be decannulated. Larynx was functional for 65.94% of the patients. The median length of follow-up was 26 months. The 5-year overall and relapse-free survival rates were respectively 59.9% and 43.4%.

CONCLUSION

Oncological and functional results confirmed the value of TORS as a treatment in previously irradiated area.

Для цитирования: Malard Olivier, Karakachoff Matilde, Ferron Christophe, Hans Stéphane, Vergez Sébastien, Garrel Renaud, Gorphe Philippe, Ramin Lionel, Santini Laure, Villeneuve Alexandre, Lasne-Cardon Audrey, Espitalier Florent, Hounkpatin Audrey. Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter GETTEC group study.. Cancer medicine. 2024. DOI: 10.1002/cam4.7031.

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