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DOI 10.3390/polym14245475

Медицинская библиотека · Polymers · 2022

Promising Role of Silk-Based Biomaterials for Ocular-Based Drug Delivery and Tissue Engineering.

Wani Shahid Ud Din, Masoodi Mubashir Hussain, Gautam Surya Prakash, Shivakumar H G, Alshehri Sultan, Ghoneim Mohammed M, Alam Prawez, Shakeel Faiyaz

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Аннотация

Silk is a wonderful biopolymer that has a long history of medical applications. Surgical cords and medically authorised human analogues made of silk have a long history of use in management. We describe the use of silk in the treatment of eye diseases in this review by looking at the usage of silk fibroin for eye-related drug delivery applications and medication transfer to the eyes. During this ancient art endeavour, a reduced engineering project that employed silk as a platform for medicine delivery or a cell-filled matrix helped reignite interest. With considerable attention, this study explores the present usage of silk in ocular-based drug delivery. This paper also examines emerging developments with the use of silk as a biopolymer for the treatment of eye ailments. As treatment options for glaucoma, diabetic retinopathy, retinitis pigmentosa, and other retinal diseases and degenerations are developed, the trans-scleral route of drug delivery holds great promise for the selective, sustained-release delivery of these novel therapeutic compounds. We should expect a swarm of silk-inspired materials to enter clinical testing and use on the surface as the secrets of silk are unveiled. This article finishes with a discussion on potential silk power, which adds to better ideas and enhanced ocular medicine delivery.

Для цитирования: Wani Shahid Ud Din, Masoodi Mubashir Hussain, Gautam Surya Prakash, Shivakumar H G, Alshehri Sultan, Ghoneim Mohammed M, Alam Prawez, Shakeel Faiyaz. Promising Role of Silk-Based Biomaterials for Ocular-Based Drug Delivery and Tissue Engineering.. Polymers. 2022. DOI: 10.3390/polym14245475.
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