[Immunoregulation effect of traditional Chinese medicine treatment on patients with oral lichen planus].

OBJECTIVE

To explore effect of traditional Chinese medicine (TCM) treatment on immune state of patients with oral lichen planus (OLP).

METHODS

30 cases of patients with OLP were treated by TCM and peripheral blood T-lymphocyte subgroup in these patients were determined.

RESULTS

CD3, CD4 and CD4/CD3 ratio of patients with OLP were decreased significantly, compared with that of health people (P < 0.01) before TCM treatment, while after TCM treatment CD3, CD4 and CD4/CD3 ratio were increased significantly (P < 0.01) and the latter recovered to normal, 8 patients recovered, 14 cases significantly improved, and 8 cases improved.

CONCLUSION

TCM therapy is useful for the treatment of OLP. It acts biphasically a regulation effect on the immunologic balance of the patient.