The clinical challenge of onychomycosis.

Onychomycosis continues to be a difficult diagnosis to establish and treat. Better testing modalities need to be developed. Although new antimycotic agents [table: see text] are far more promising than previous treatments, relapse rates remain high. Patient education must be a mainstay of therapy. Establishing realistic expectations, providing a detailed treatment plan with follow-up, and reviewing preventive measures will enhance patient satisfaction and improve cure rates.