Revista da Sociedade Brasileira de Medicina Tropical · 2021
Determinants of minute ventilation-carbon dioxide production relationship in Chagas cardiomyopathy.
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Oliveira Lucas Frois Fernandes, Andrade Janaina Martins, Figueiredo Pedro Henrique Scheidt, Ávila Matheus Ribeiro, Silva Whesley Tanor, Vianna Marcus Vinicius Accetta, Trede Filho Renato Guilherme, Costa Henrique Silveira, Rocha Manoel Otávio Costa, Lima Vanessa Pereira
Аннотация
INTRODUCTION: The minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) is among the main prognostic factors of Chagas cardiomyopathy whose determinants remain unknown.
METHODS: Seventy-eight patients with Chagas cardiomyopathy were evaluated using clinical assessment, cardiopulmonary exercise test, echocardiography, and International Physical Activity Questionnaire.
RESULTS: Age, functional class, International Physical Activity Questionnaire score, and dilated cardiomyopathy with systolic dysfunction were independent determinants of VE/VCO2 slope, and these variables explained 63% of its variance.
CONCLUSIONS: The VE/VCO2 slope was related to age, functional class, physical activity level, and dilated cardiomyopathy with systolic dysfunction in patients with Chagas cardiomyopathy.
METHODS: Seventy-eight patients with Chagas cardiomyopathy were evaluated using clinical assessment, cardiopulmonary exercise test, echocardiography, and International Physical Activity Questionnaire.
RESULTS: Age, functional class, International Physical Activity Questionnaire score, and dilated cardiomyopathy with systolic dysfunction were independent determinants of VE/VCO2 slope, and these variables explained 63% of its variance.
CONCLUSIONS: The VE/VCO2 slope was related to age, functional class, physical activity level, and dilated cardiomyopathy with systolic dysfunction in patients with Chagas cardiomyopathy.