Eruptive syringoma of the penis. A report of 2 cases and a review of the literature.

Syringoma exclusively located to the penis is an extraordinary rare dermatological condition, and only 6 patients with syringoma exclusively located to the penis have been published previously. Light microscopical examination of routine hematoxylin and eosin-stained sections from punch biopsies with adequate depth from 2 patients was performed. Classical syringoma was diagnosed. The lesions occurred in an eruptive fashion in both patients on the dorsal and lateral aspects of the penis shaft. There was a variation in clinical appearances ranging from yellow-white papules, a few millimeter in size to, in one of the patients, formation of several slightly elevated plaques, 10 mm in size, with a brownish-red color. We describe clinicopathological features of 2 patients with syringoma exclusively located to the penis. These are compared with all the previously published cases. Clinical and histopathological differential diagnoses are discussed, and a literature review is presented.