Cancer research and treatment · 2016
Treatment of Pulmonary Tumor Embolism from Choriocarcinoma: Extracorporeal Membrane Oxygenation as a Bridge through Chemotherapy.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Chung Jae Heun, Yeo Hye Ju, Cho Hyun Myung, Jang Jin Ook, Ye Byung Min, Yoon Gun, Shin Dong Hoon, Kim Dohyung, Cho Woo Hyun
Аннотация
A 22-year-old woman with a 1-month history of shortness of breath that was treated as a case of tuberculosis and pulmonary embolism was referred to the authors' hospital. Because of the hemodynamic instability in this patient, venoarterial extracorporeal membrane oxygenation (ECMO) was administered in the intensive care unit. She underwent a pulmonary embolectomy for the treatment of progressive circulatory collapse secondary to a pulmonary embolism. The histopathologic result was consistent with a metastatic choriocarcinoma. Despite the surgical management, persistent refractory cardiogenic shock occurred. Subsequently, the patient was treated with chemotherapy in the presence of ECMO and responded well to chemotherapy. She was discharged after 3 months. This case suggests that metastatic choriocarcinoma should be considered as a differential diagnosis in women of childbearing age presenting with a pulmonary embolism, and ECMO may be beneficial in patients with pulmonary embolism for bridging to surgical embolectomy and chemotherapy.
Предметные рубрики MeSH
Antineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorBlood Gas AnalysisChoriocarcinomaComputed Tomography AngiographyExtracorporeal Membrane OxygenationFemaleHumansImmunohistochemistryNeoplasm StagingNeoplastic Cells, CirculatingPulmonary EmbolismTomography, X-Ray ComputedTreatment OutcomeYoung Adult