Influence of Life Satisfaction on Quality of Life: Mediating Roles of Depression and Anxiety Among Cardiovascular Disease Patients.

The present study aimed to determine the mediating effects of depression and anxiety on the association between life satisfaction and quality of life. We used the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), and EuroQol Five Dimensions Questionnaire (EQ-5D) to measure depression, anxiety, and quality of life, respectively. A single question was used to measure the life satisfaction of participants. Life satisfaction was significantly related with depression (r = -0.17), anxiety (r = -0.18), and quality of life (r = 0.19). Depression and anxiety were also related to quality of life. Depression and anxiety had full mediating effects (β = -0.274; β = -0.208) on the association between life satisfaction and quality of life. For those with poor life satisfaction, people were more likely to have high level of depression and anxiety, which in turn experienced poor quality of life.