Медицинская библиотека · Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2005

Effects of single herbal drugs on adhesion and migration of melanocytes.

Zhang Xianqi, Feng Jie, Mu Kuanhou, Ma Huiqun, Niu Xinwu, Liu Chao, Dang Qianli

СтатьяПеревод пока не подготовлен

Аннотация

OBJECTIVE

To find herbs with effects on adhesion and migration of melanocytes in vitro.

MATERIALS AND

METHODS

Ethanol extracts from 14 herbs were tested. Normal human melanocytes were obtained from neonatal foreskin, and the 48-well culture dish covered with fibronectin was used for the melanocyte adhesion assay. Motility was assessed by using the micropore filter method.

RESULTS

The extracts of Danshen (Radix Salviae Miltiorrhizae), Tusizi (Semen Cuscutae) and Honghua (Flos Carthami) could enhance melanocyte adhesion to fibronectin, while Cijili (Fructus Tribuli) and Huangqi (Radix Astragali) promote melanocyte migration in vitro. Buguzhi (Fructus Psoraleae), Nü Zhen Zi (Fructus Ligustri Lucidi) and Baizhi (Radix Angelicae Dahuricae) could promote both adhesion and migration of melanocytes.

CONCLUSION

The above herbs may play a role through promoting adhesion and/or migration of melanocytes in the treatment of vitiligo.

Для цитирования: Zhang Xianqi, Feng Jie, Mu Kuanhou, Ma Huiqun, Niu Xinwu, Liu Chao, Dang Qianli. Effects of single herbal drugs on adhesion and migration of melanocytes.. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2005.

Предметные рубрики MeSH

Cell Adhesion Cell Movement Cells, Cultured Drugs, Chinese Herbal Humans Infant, Newborn Melanocytes Skin Vitiligo

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