Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia · 2006
[High relationship between ciprofloxacin use and prevalence of ESBL Klebsiella pneumoniae].
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Bermejo Joaquín, Bencomo Blanca, Arnesi Nora, Lesnaberes Patricia, Borda Noemí, Notario Rodolfo
Аннотация
BACKGROUND: To assess the relationship between ciprofloxacin use and the prevalence of extended spectrum betalactamases (ESBL) Klebsiella pneumoniae.
PATIENTS AND METHODS: Semestral mean values regarding use of antibiotic and prevalence of ESBL Kp were compared during 9 semesters using linear regression and coefficient of correlation.
RESULTS: The only statistically significant correlation was ciprofloxacin use and ESBL(+) K. pneumoniae prevalence, with a coefficient of correlation of 0.86 and p = 0.0027 using linear regression.
CONCLUSIONS: Ciprofloxacin use must be taking into account when considering infection control programs due to high prevalence rates of ESBL(+) K. pneumoniae in the hospital setting.
PATIENTS AND METHODS: Semestral mean values regarding use of antibiotic and prevalence of ESBL Kp were compared during 9 semesters using linear regression and coefficient of correlation.
RESULTS: The only statistically significant correlation was ciprofloxacin use and ESBL(+) K. pneumoniae prevalence, with a coefficient of correlation of 0.86 and p = 0.0027 using linear regression.
CONCLUSIONS: Ciprofloxacin use must be taking into account when considering infection control programs due to high prevalence rates of ESBL(+) K. pneumoniae in the hospital setting.