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Retina (Philadelphia, Pa.) · 2025

YAG Laser-Assisted Fragmentation of Dexamethasone Implants in the Anterior Chamber.

СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Meduri Alessandro, De Luca Laura, Oliverio Giovanni William, Mancini Maura, Grenga Pierluigi, Fragiotta Serena, Carlà Matteo Mario, Aragona Pasquale

Аннотация

PURPOSE: To report efficacy on the use of neodymium yag laser in fragmentating dexamethasone intravitreal implant (Ozurdex, Allergan, Inc, Irvine, CA) migrated in the anterior chamber (AC).

METHODS: Multicenter, retrospective, interventional case series of 10 patients treated with Nd:Yag laser following spontaneous migration of dexamethasone implant into the AC.

RESULTS: The Nd:yag laser successfully fragmented the migrated implants in all cases without severe complications. No patient exhibited corneal edema at 4 months post-treatment. Visual acuity remained stable or improved in four patients, while one patient had minimal transient visual deterioration due to pre-existing retinal conditions. In all patients resolution of previous macular edema was detected.

CONCLUSIONS: Spontaneous migration of the dexamethasone intravitreal implant into the anterior chamber can occur in patients with aphakia, prior pars plana vitrectomy, or compromised capsular support. Timely intervention using Nd:yag laser can effectively fragment the dexamethasone implant, mitigating the risk of corneal endothelial damage and preserving visual function. In this cohort Nd:yag laser appeared a safe and effective treatment option for managing anterior chamber migration of the dexamethasone intravitreal implant, avoiding the need for more invasive surgical techniques or temporary non-invasive techniques.