Late effects and cosmetic results of simultaneous integrated boost versus sequential boost after conventional irradiation in breast-conserving therapy; out come of 7 months follow-up.

OBJECTIVE

To compare simultaneous integrated boost and sequential boost after conventional irradiation in breast-conserving therapy in aspect of late effects and cosmetic results.

MATERIAL AND METHOD: Between August 2006 and June 2007, 60 breasts were treated in this prospective nonrandomized study, designed to compare simultaneous integrated boost (additional 10 Gy/25F) and sequential boost (15 Gy/5F) to the tumor bed in terms of late effects and cosmetic results at 7-month and 3-year follow-up. Pearson Chi-square test was used, with an a-value of 0.05.

RESULTS

Hyper/hypopigmentation and induration/fibrosis were commonly seen at 7-months follow-up (p = 0.84 and 0.83, respectively). The cosmetic results were good or excellent.

CONCLUSION

Although the present study included a small number of patients and short follow-up time, the preliminary results were comparable between the study groups.