[Disseminated zygomycosis in patients with acute leukemia].

The authors present two patients with acute myeloid leukaemia and pulmonary-disseminated form of zygomycosis developed during the period of bone marrow aplasia. Diagnosis was established on necropsy on the basic of the patho-histological finding of wide, short and nonseptate hyphe with irregular branching. Hyphe were clearly recognized on Gomori methenamine Silver stained preparations. There were multiple haemorrhagic-necrotic infarcts of different organs due to the mycotic invasion of blood vessels. The authors discuss some some important diagnostic and therapeutic problems.