Hypothalamic-pituitary axis deficiency following traumatic brain injury in a dog.

OBJECTIVE

To describe endocrine dysfunction associated with traumatic brain injury in a dog.

SUMMARY: A 12-week-old dog presented with traumatic brain injury and did not respond to traditional supportive care. Continued hypothermia, electrolyte derangements, hypotension, and hyposthenuria prompted screening for and detection of several hypothalamic-pituitary disorders including: hypoadrenocorticism, central diabetes insipidus, hypothyroidism, and growth hormone deficiency. Electrolyte abnormalities, urine osmolarity, and blood pressure improved with treatment for the associated disorders.

NEW OR UNIQUE INFORMATION PROVIDED: This is the first report of generalized hypothalamic-pituitary dysfunction or panhypopituitarism following traumatic brain injury in a dog.