Clinical neurology and neurosurgery · 2017
Blood blister-like aneurysms in Tibetans: A retrospective observational study.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chen Ruiqi, Xiao Anqi, Li Hao, Ma Lu, Lin Sen, You Chao
Аннотация
OBJECT: Although research on blood blister-like aneurysms (BLAs) in different population is well documented, studies of that in the plateau area remain elusive. This study aimed to develop a better understanding of BLAs in Tibetan population, which is a typical representation of people in plateau area.
METHODS: In this retrospective observational study, the hospital information system (HIS) was used to search for consecutive patients with BLAs by using the discharge diagnoses. A total of 19 Tibetan patients and 34 Han patients were recruited from January 2012 to January 2016. Intra-hospital and follow-up data were collected and compared between two races.
RESULTS: Compared with Han group, Tibetan group got significantly higher ratio of BLAs among aneurysmal subarachnoid hemorrhages (aSAHs) (19.6% (19/97) vs 3.2% (34/1071), p<0.001), higher Incidence of atypical located BLAs (26.3% vs 2.9%, p=0.034), higher risk of cerebral infarction (63.2% vs 11.8%, p<0.001), and greater number of patients with unfavorable outcomes at 6 months after ictus (57.9% vs 23.5%, p=0.028). In Tibetan group, patients underwent endovascular treatment presented with significantly lower cerebral infarction rate (p=0.019) and better neurological functional recovery outcome (p=0.048) compared with surgical group.
CONCLUSIONS: Compared with Han patients, Tibetan BLA patients presented with high risk of occurrence with atypical locations and high incidence of cerebral infarctions with poor prognoses. Endovascular treatment benefits more for Tibetan BLA patients in reducing cerebral infarctions and improving neurological functional recovery prognosis.
METHODS: In this retrospective observational study, the hospital information system (HIS) was used to search for consecutive patients with BLAs by using the discharge diagnoses. A total of 19 Tibetan patients and 34 Han patients were recruited from January 2012 to January 2016. Intra-hospital and follow-up data were collected and compared between two races.
RESULTS: Compared with Han group, Tibetan group got significantly higher ratio of BLAs among aneurysmal subarachnoid hemorrhages (aSAHs) (19.6% (19/97) vs 3.2% (34/1071), p<0.001), higher Incidence of atypical located BLAs (26.3% vs 2.9%, p=0.034), higher risk of cerebral infarction (63.2% vs 11.8%, p<0.001), and greater number of patients with unfavorable outcomes at 6 months after ictus (57.9% vs 23.5%, p=0.028). In Tibetan group, patients underwent endovascular treatment presented with significantly lower cerebral infarction rate (p=0.019) and better neurological functional recovery outcome (p=0.048) compared with surgical group.
CONCLUSIONS: Compared with Han patients, Tibetan BLA patients presented with high risk of occurrence with atypical locations and high incidence of cerebral infarctions with poor prognoses. Endovascular treatment benefits more for Tibetan BLA patients in reducing cerebral infarctions and improving neurological functional recovery prognosis.