Медицинская библиотека · International immunopharmacology · 2025

MicroRNAs in patients with pemphigus: A systematic review.

Razavi Zahra, Esmaeili Nafiseh, Katebian Saba, Aryanian Zeinab, Mosayebi Fatemeh, Hemmati Delnia Namdari, Kianfar Nika, Shakoei Safoura

СтатьяСистематический обзорПеревод в очереди

Аннотация

BACKGROUND

Pemphigus is a group of rare and severe autoimmune blistering diseases (AIBDs). MicroRNA's role in the pathogenesis of pemphigus disease has been previously studied, but MicroRNAmicroRNAs research in dermatology is still at its beginning.

METHODS

This review was carried out using a systematic search on PubMed, Scopus Embase, and Web of Science from 1990 to February 2025 to explore the role of microRNA in the diagnosis and severity evaluation of pemphigus disease.

RESULTS

A total of 8 studies were identified in the systematic review that indicated the expression level of 18 types of microRNA was significantly different from that of healthy people.

CONCLUSIONS

The collective data presented in this review indicate that MicroRNAmicroRNAs may help diagnose and predict the course of pemphigus, while the clinical application of these findings has yet to be verified.

Для цитирования: Razavi Zahra, Esmaeili Nafiseh, Katebian Saba, Aryanian Zeinab, Mosayebi Fatemeh, Hemmati Delnia Namdari, Kianfar Nika, Shakoei Safoura. MicroRNAs in patients with pemphigus: A systematic review.. International immunopharmacology. 2025. DOI: 10.1016/j.intimp.2025.114606.

Предметные рубрики MeSH

Humans Biomarkers MicroRNAs Pemphigus

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