Clinical radiology · 2025
Reduction of radiation dose and contrast medium volume in computed tomography pulmonary angiography: adaptation of dual-energy computed tomography (CT) protocols to the body mass index.
СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Zhang X, Huang H, Huang Y, Sun Y, Chen Z, Chen M, Xu J
Аннотация
AIM: To evaluate the image quality and diagnostic value of a body mass index (BMI)-based dual-energy computed tomography (CT) protocol in computed tomography pulmonary angiography (CTPA) for reduction of radiation dose and contrast medium (CM) volume.
MATERIALS AND METHODS: Patients suspected of having pulmonary embolism were prospectively included and randomly assigned to one of three protocols: Protocol A (a standard protocol, 100 kV/140 mAs/50 mL iodinated CM), B (a conventional dual-energy protocol, 80-140 kV switching/automatic tube current/weight-dependent CM volume) and C (a BMI-based dual-energy protocol, 80-140 kV switching/BMI-based tube current/weight-dependent CM volume, BMI-based CM injection rate). Subjective and objective image analysis were performed by two radiologists independently. Diagnostic accuracy of pulmonary embolism were evaluated. Inter-group comparison was performed.
RESULTS: Ninety patients (mean age 54.1 ± 13.3 years, 57 men) were included, with 30 patients in each group. The CT values, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) of the pulmonary arteries in group C were significantly higher than those in group B (358.2 ± 50.5 vs 324.9 ± 57.2, p=0.047, 17.8 ± 3.2 vs 15.3 ± 2.9, p=0.010, 19.2 ± 4.1 vs 15.7 ± 3.8, p=0.014). The dose length product (DLP) and CM volume were significantly reduced in groups B and C (A vs B vs C, DLP, 287.9 ± 34.0 vs 177.2 ± 39.2 vs 183.8 ± 23.1 mGy·cm), p<0.001, CM, 50.0 ± 0.0 vs 22.1 ± 3.0 vs 23.2 ± 4.0 ml, p<0.001). There were no significant differences in diagnostic accuracy or subjective image quality among the three groups.
CONCLUSION: The BMI-based dual-energy CT protocol can reduce radiation exposure and iodine burden compared to routine CTPA without affecting the image quality and diagnostic accuracy in patients with a BMI under 30 kg/m2.
MATERIALS AND METHODS: Patients suspected of having pulmonary embolism were prospectively included and randomly assigned to one of three protocols: Protocol A (a standard protocol, 100 kV/140 mAs/50 mL iodinated CM), B (a conventional dual-energy protocol, 80-140 kV switching/automatic tube current/weight-dependent CM volume) and C (a BMI-based dual-energy protocol, 80-140 kV switching/BMI-based tube current/weight-dependent CM volume, BMI-based CM injection rate). Subjective and objective image analysis were performed by two radiologists independently. Diagnostic accuracy of pulmonary embolism were evaluated. Inter-group comparison was performed.
RESULTS: Ninety patients (mean age 54.1 ± 13.3 years, 57 men) were included, with 30 patients in each group. The CT values, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) of the pulmonary arteries in group C were significantly higher than those in group B (358.2 ± 50.5 vs 324.9 ± 57.2, p=0.047, 17.8 ± 3.2 vs 15.3 ± 2.9, p=0.010, 19.2 ± 4.1 vs 15.7 ± 3.8, p=0.014). The dose length product (DLP) and CM volume were significantly reduced in groups B and C (A vs B vs C, DLP, 287.9 ± 34.0 vs 177.2 ± 39.2 vs 183.8 ± 23.1 mGy·cm), p<0.001, CM, 50.0 ± 0.0 vs 22.1 ± 3.0 vs 23.2 ± 4.0 ml, p<0.001). There were no significant differences in diagnostic accuracy or subjective image quality among the three groups.
CONCLUSION: The BMI-based dual-energy CT protocol can reduce radiation exposure and iodine burden compared to routine CTPA without affecting the image quality and diagnostic accuracy in patients with a BMI under 30 kg/m2.