How Does Social Participation Affect the Associations Between Depression, Life satisfaction, and IADL Disability in Middle-Aged and Older Adults? A Longitudinal Mediation and Moderation Model.

This study examined the longitudinal associations and mechanisms between Instrumental Activities of Daily Living (IADL) disability and depression among middle-aged and older adults. Using data from three waves (2015, 2018, 2020) of the China Health and Retirement Longitudinal Study (CHARLS), a cross-lagged model was employed. It revealed that IADL disability predicted depression, with life satisfaction as a mediator. Social participation trajectory moderated these longitudinal associations, with a higher trajectory reducing negative effects of IADL disability on depression by enhancing life satisfaction. The findings suggest that promoting social participation to improve life satisfaction may help prevent depression associated with IADL disability.