Ocular immunology and inflammation · 2025
Anterior Segment Involvement in Polycythemia Vera: A Case Report and Review of Literature.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Bruno Rocco, Bolletta Elena, Gozzi Fabrizio, Gentile Pietro, De Simone Luca, Mastropasqua Rodolfo, Cimino Luca
Аннотация
PURPOSE: To describe the clinical and tomographic features of anterior segment involvement as the initial manifestation of previously undiagnosed Polycythemia Vera (PV), using slit-lamp examination and anterior segment optical coherence tomography (AS-OCT) before and after treatment.
METHODS: Observational case report and literature review of ocular involvement in PV.
RESULTS: A 42-year-old Caucasian woman presented with a long-standing history of unilateral conjunctival and episcleral hyperemia and vascular tortuosity unresponsive to topical therapy, showing clinical features inconsistent with ocular inflammation. Slit-lamp examination revealed conjunctival and episcleral vascular congestion that did not blanch with phenylephrine drops. AS-OCT imaging demonstrated ectasia and dilatation of the superficial and deep episcleral vascular plexuses. Laboratory work-up confirmed a diagnosis of PV. Following initiation of appropriate therapy, the episcleral vascular hyperemia and engorgement fully resolved without residual sequelae. A review of the literature identified two cases reported between 1971 and the present. Their presentations and clinical courses are reviewed herein.
CONCLUSIONS: This report characterizes anterior segment involvement in PV using slit-lamp and AS-OCT imaging, highlights its distinctive clinical features, and underscores the importance of laboratory investigations in evaluating atypical ocular presentations potentially caused by hematological masquerade disorders.
METHODS: Observational case report and literature review of ocular involvement in PV.
RESULTS: A 42-year-old Caucasian woman presented with a long-standing history of unilateral conjunctival and episcleral hyperemia and vascular tortuosity unresponsive to topical therapy, showing clinical features inconsistent with ocular inflammation. Slit-lamp examination revealed conjunctival and episcleral vascular congestion that did not blanch with phenylephrine drops. AS-OCT imaging demonstrated ectasia and dilatation of the superficial and deep episcleral vascular plexuses. Laboratory work-up confirmed a diagnosis of PV. Following initiation of appropriate therapy, the episcleral vascular hyperemia and engorgement fully resolved without residual sequelae. A review of the literature identified two cases reported between 1971 and the present. Their presentations and clinical courses are reviewed herein.
CONCLUSIONS: This report characterizes anterior segment involvement in PV using slit-lamp and AS-OCT imaging, highlights its distinctive clinical features, and underscores the importance of laboratory investigations in evaluating atypical ocular presentations potentially caused by hematological masquerade disorders.