[Alterations of the fundus in the sense of a "flecked retina" in onchocerciasis (author's transl)].

Onchocerciasis is one of the main reasons of blindness in aequatorial Africa. In 50 patients suffering from onchocerciasis fluoangiograms of the eye fundus have been studied. After the treatment of onchocerciasis we often found changes similar to those of a "flecked retina". The angiographic observations demonstrated that the alterations are to be localised into the pigmented epithelium of the retina. Furthermore these alterations which are similar to a "retinitis punctata albescens" are interpreted as the result of a antigen-antibody reaction of the uveal tract. This reaction is due to deliberated endotoxins of dead microfilaria.