Fertility preservation by ex vivo oocyte retrieval in a 17-year-old with bilateral borderline ovarian tumors: a case report.

We report a case of fertility preservation through ex vivo oocyte aspiration in an adolescent who underwent bilateral oophorectomy due to asynchronous borderline ovarian tumors. A 17-year-old nulligravid patient was initially diagnosed with a left-sided serous borderline ovarian tumor and treated with left salpingo-oophorectomy. One year later, a lesion was identified in the contralateral ovary, with surgical indication for salpingo-oophorectomy. Ovarian stimulation was performed using recombinant FSH and hMG, with final oocyte maturation triggered by a GnRH agonist. Oocyte retrieval was conducted ex vivo, immediately after surgical removal of the ovary. A total of 13 oocytes were obtained, 10 of which were in metaphase II and successfully cryopreserved. This case highlights the feasibility and efficacy of ex vivo oocyte retrieval as a fertility preservation strategy in oncology patients requiring urgent bilateral oophorectomy.