Revista da Sociedade Brasileira de Medicina Tropical · 2007
Morbidity due to Schistosoma mansoni--Entamoeba histolytica coinfection in hamsters (Mesocricetus auratus).
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Dolabella Silvio Santana, Coelho Paulo Marcos Zech, Borçari Izabela Torquetti, Mello Nelson Azevedo Santos Teixeira, Andrade Zilton de Araújo, Silva Edward Felix
Аннотация
Data on Schistosoma mansoni-Entamoeba histolytica coinfection are scarce in the literature. In the present study, hamsters that had been infected for 70 days with Schistosoma mansoni (LE strain) were inoculated via the portal vein with two strains of trophozoites of Entamoeba histolytica: ICB-EGG (highly virulent) and ICB-RPS (non-virulent). The most evident result of coinfection was increased morbidity and mortality, in comparison with either of the infections alone. Histologically, there were no evident signs of interaction between these two infections. The morphological findings of schistosomal granuloma and amoebic abscesses in the liver were similar to those seen in the respective single-infection controls. However, there was severe wasting of the animals with both infections and greater numbers of amoebic lesions in their livers. The results obtained indicated that schistosomiasis aggravates the course of amoebiasis in hamsters.