Acta anaesthesiologica Scandinavica · 2014
Dabigatran anticoagulation and Stanford type A aortic dissection: lethal coincidence: Case report with literature review.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Stein P, Bosshart M, Brand B, Schlicker A, Spahn D R, Bettex D
Аннотация
BACKGROUND: Novel oral anticoagulants are now encountered in patients needing emergency surgery. Knowledge and treatment options are limited.
METHODS AND RESULT: We present the case of a 76-year-old patient who suffered from an acute Stanford type A aortic dissection, needing emergency surgical aortic repair. He was anticoagulated with dabigatran due to past atrial fibrillation. Despite haemodiafiltration, surgical revision and massive transfusion of packed red blood cells, fresh frozen plasma, platelets, coagulation factors, and recombinant factor VIIa, the patient died from intractable bleeding with sustained therapeutic levels of dabigatran.
CONCLUSION: After reviewing the literature, we summarize the limited treatment options and show possible approaches for patients treated with dabigatran needing emergency surgery.
METHODS AND RESULT: We present the case of a 76-year-old patient who suffered from an acute Stanford type A aortic dissection, needing emergency surgical aortic repair. He was anticoagulated with dabigatran due to past atrial fibrillation. Despite haemodiafiltration, surgical revision and massive transfusion of packed red blood cells, fresh frozen plasma, platelets, coagulation factors, and recombinant factor VIIa, the patient died from intractable bleeding with sustained therapeutic levels of dabigatran.
CONCLUSION: After reviewing the literature, we summarize the limited treatment options and show possible approaches for patients treated with dabigatran needing emergency surgery.
Предметные рубрики MeSH
AgedAortic DissectionAnticoagulantsAortic Aneurysm, ThoracicAortic Valve InsufficiencyAtrial FibrillationBenzimidazolesBlood Coagulation FactorsBlood Coagulation TestsBlood Component TransfusionCardiac TamponadeCardiopulmonary BypassDabigatranEmergenciesFatal OutcomeHeart Valve Prosthesis ImplantationHemodiafiltrationHeparinHumansHypertensionHypertrophy, Left VentricularMalePyridinesShock, HemorrhagicThrombelastographyTranexamic Acid