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DOI 10.1016/j.ejso.2005.11.019

Медицинская библиотека · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2006

Outcome following lung resections for pT1 non-small cell lung cancer.

Kopp R, Weidenhagen R, Reinmiedl J, Müller C, Fürst H, Bittmann I, Dienemann H, Hatz R

Сравнительное исследованиеСтатьяПеревод пока не подготовлен

Аннотация

AIMS: To analyse the outcome of patients with pT1 NSCLC treated at our institution by antero-lateral thoracotomy, anatomical lung resections and mediastinal lymph node dissection between 1980 and 2001.

METHODS

Follow-up data were obtained retrospectively from 1980 to 1990 and prospectively after 1990. Survival was analysed using the Kaplan-Meier method.

RESULTS

Histopathological examinations revealed mediastinal lymph node infiltration in 27.6% (pN1 17.8% and pN2 9.8%). pN2 was classified in 14.1% of adenocarcinomas compared to 6.2% of squamous cell carcinomas. Median overall survival of patients with pT1 carcinomas was 89+16 months (median+standard error). Histopathological N-classification indicates differential prognostic and therapeutic implications in pT1 adeno- and squamous cell carcinomas.

CONCLUSIONS

Complete lymph node dissection is required for all patients with T1 NSCLC treated by either open surgery or VATS resection. Histopathological N-classification indicates differential prognostic and therapeutic implications in pT1 adeno- and squamous cell carcinomas.

Для цитирования: Kopp R, Weidenhagen R, Reinmiedl J, Müller C, Fürst H, Bittmann I, Dienemann H, Hatz R. Outcome following lung resections for pT1 non-small cell lung cancer.. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2006. DOI: 10.1016/j.ejso.2005.11.019.

Предметные рубрики MeSH

Carcinoma, Non-Small-Cell LungFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingPneumonectomyProspective StudiesRetrospective StudiesSurvival RateTime FactorsTreatment Outcome
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