Therapeutic advances in urology · 2026
Age-related differences in bladder function and sexual outcomes following bipolar transurethral resection of the prostate: a retrospective cohort study.
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Yeni Sezgin, Demir Aslan, Sabuncu Hayrettin, Yildiz Halil Emre, Ortac Hatice
Аннотация
BACKGROUND: Benign prostatic obstruction negatively affects bladder emptying and, if untreated, may be associated with impaired bladder emptying and related complications.
OBJECTIVES: To compare postoperative outcomes of bipolar transurethral resection of the prostate (bipolar TURP) among different age groups and evaluate the effect of patient age.
DESIGN: Retrospective cohort study.
METHODS: We analyzed 132 male patients who underwent bipolar TURP between May 2022 and January 2024. Patients were grouped by age: Group 1 (50-60 years), Group 2 (61-70 years), and Group 3 (⩾71 years). Pre- and postoperative parameters-including prostate-specific antigen, prostate volume, uroflowmetry (maximum and average flow rates, voided volume, post-void residual), symptom duration, medication use, and International Index of Erectile Function-5 (IIEF-5) scores-were assessed at 12 months postoperatively.
RESULTS: Group 1 demonstrated significantly greater improvements in peak flow rates, post-void residual volume, and IIEF-5 scores compared with the older cohorts (p < 0.05). While Group 3 presented with the longest symptom duration and highest medication use at baseline, multivariate regression analysis identified advancing age as an independent predictor of more limited improvement in post-void residual volume (p = 0.008) and IIEF-5 scores (p < 0.001), while its association with ∆Qmax reached only marginal significance (p = 0.050). Younger patients exhibited better postoperative preservation of erectile function and relatively improved recovery of bladder emptying.
CONCLUSION: Patient age is associated with urinary and sexual outcomes after bipolar TURP. The strongest age-related associations were observed for postoperative recovery of bladder emptying and preservation of erectile function, whereas improvement in peak flow rate was less strongly age-dependent and should be interpreted with caution.
TRIAL REGISTRATION: Not applicable.
OBJECTIVES: To compare postoperative outcomes of bipolar transurethral resection of the prostate (bipolar TURP) among different age groups and evaluate the effect of patient age.
DESIGN: Retrospective cohort study.
METHODS: We analyzed 132 male patients who underwent bipolar TURP between May 2022 and January 2024. Patients were grouped by age: Group 1 (50-60 years), Group 2 (61-70 years), and Group 3 (⩾71 years). Pre- and postoperative parameters-including prostate-specific antigen, prostate volume, uroflowmetry (maximum and average flow rates, voided volume, post-void residual), symptom duration, medication use, and International Index of Erectile Function-5 (IIEF-5) scores-were assessed at 12 months postoperatively.
RESULTS: Group 1 demonstrated significantly greater improvements in peak flow rates, post-void residual volume, and IIEF-5 scores compared with the older cohorts (p < 0.05). While Group 3 presented with the longest symptom duration and highest medication use at baseline, multivariate regression analysis identified advancing age as an independent predictor of more limited improvement in post-void residual volume (p = 0.008) and IIEF-5 scores (p < 0.001), while its association with ∆Qmax reached only marginal significance (p = 0.050). Younger patients exhibited better postoperative preservation of erectile function and relatively improved recovery of bladder emptying.
CONCLUSION: Patient age is associated with urinary and sexual outcomes after bipolar TURP. The strongest age-related associations were observed for postoperative recovery of bladder emptying and preservation of erectile function, whereas improvement in peak flow rate was less strongly age-dependent and should be interpreted with caution.
TRIAL REGISTRATION: Not applicable.