[The mode of prognosis course of gastric ulcer].

The stomach ulcer is widely spread and is characterized by dangerous and now and then lethal complications. The study was carried out to develop mode of prognosis of course of stomach ulcer. The complex examination of 40 healthy volunteers (control group) and 42 patients with stomach ulcer (main group)was implemented. All participants gave informed consent. In blood serum of examined persons using immune enzyme technique the concentration of secretory immunoglobulin A (sIgA), pepsinogen-II (PG-II) and cancer antigen 72-4 (CA 72-4) were detected. The results were statistically processed. In patients levels of sIgA and PG-II exceeded upper limits of normal values in 90.5% and 61.9% of cases correspondingly and depended on course of disease. The level CA 72-4 was higher of upper limit of normal values in all patients with severe course and frequent exacerbations of stomach ulcer. The detected in patients significant alterations of sIgA, PG-II, CA 72-4 permit to recommend detection of the given combination of indices for prognosis of course of stomach ulcer.