Personalized Thyroidology: Molecular Rewiring of Thyroid Nodule Management.

Multigene molecular testing panels demonstrated excellent performance characteristics for the evaluation of indeterminate thyroid nodules and independently risk-stratified advanced tumor stage in the Chinese population. Findings support incorporating cost-conscious molecular diagnostics in an integrated pathway along with clinical, sonographic, and cytologic features while underscoring the need for prospective validation in future studies. See related article by Ding et al., p. 4996.