Simultaneous Liver and Kidney Transplantation for Cirrhosis Directly Attributed to Disseminated Hepatic Coccidioidomycosis.

Disseminated coccidioicomycosis can have devastating consequences following immunosuppression. Herein, we describe a kidney transplant recipient with subsequent allograft rejection and graft loss, who developed disseminated hepatic cocccidioidomycosis that led to progressive hepatic fibrosis and cirrhosis. He then underwent simultaneous liver and kidney transplantation while maintaining antifungal therapy. No other etiology for cirrhosis was determined following extensive testing that included his explanted liver.