Gan to kagaku ryoho. Cancer & chemotherapy · 2014
[A case of cecum colon cancer with lymph node metastasis successfully treated with XELOX plus bevacizumab].
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
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Ito Shingo, Ichikawa Ryosuke, Kure Kazumasa, Honjo Kumpei, Aoki Jun, Okazawa Yu, Mizukoshi Kosuke, Ro Hisashi, Kawai Masaya, Takehara Kazuhiro, Okubo Haruna, Ishiyama Shun, Sugimoto Kiichi, Komiyama Hiromitsu, Takahashi Makoto, Yaginuma Yukihiro, Kojima Yutaka, Goto Michitoshi, Tomiki Yuichi, Sakamoto Kazuhiro
Аннотация
A 65-year-old woman with a history of constipation presented at our hospital and was subsequently diagnosed with advanced cecum cancer. We performed laparoscopic right hemicolectomy in January 2009, with pathological findings reveal- ing the presence of Stage III b (pT3, pN3, cM0, Cur A) disease. The patient was treated with a uracil/tegafur plus Leucovorin (UFT/LV) adjuvant chemotherapy regimen for six months. In June 2010, bold examination indicated an elevated level of tumor marker CA19-9. Computed tomography (CT) and positron emission tomography (PET)/CT revealed Virchow's and para-aortic lymph node metastasis. Therapy with XELOX and bevacizumab (Bmab) was administered and continued for 10 cycles. Capecitabine+Bmab treatment was also administered for 11 courses due to an adverse event of peripheral neuropathy. Follow-up revealed both the Virchow's and para-aortic lymph node metastasis had disappeared upon completion of treatment. In November, 2011 the patient was considered to have achieved a clinical complete response (CR) and continues to be followed with no further disease progression.